Bened Biomedical’s "Sleep-Aiding Probiotic PS150™" Wins the 22nd National Innovation Award

December 26th, 2025 | Friday

Bened Biomedical has announced that its latest R&D breakthrough, the "Sleep-Aid Probiotic PS150™ (Limosilactobacillus fermentum PS150™)," has been awarded the 22nd National Innovation Award – Enterprise Innovation Award. Standing out from numerous competitors due to its exceptional innovative mechanism and solid scientific evidence, this achievement marks another major milestone following the success of PS128™, further solidifying the company’s leadership in the global field of psychobiotics.

National Recognition: The "Oscars" of the Biotech Industry

Organized by the Institute for Biotechnology and Medicine Industry (IBMI), the "National Innovation Award" is the most prestigious honor in Taiwan’s biotech and medical sector. The award invites a panel of top domestic scholars and clinical physicians to rigorously review technical innovation, empirical data, and market application value. Bened Biomedical’s win signifies that the R&D achievements of PS150 have reached a leading international standard.

Scientific Decoding: A Sleep Savior from the "Gut"

Distinguished from general sleep aids on the market, PS150 is a breakthrough resulting from Bened Biomedical’s focus on gut-brain axis research. The R&D team has confirmed through multiple preclinical and clinical trials that PS150 effectively regulates sleep-related neurotransmitters:

• Regulating Sleep Mechanisms: Studies show PS150 inhibits the activation of wake-promoting orexinergic neurons and increases GABA levels in the cerebral cortex, helping the brain "power down" into a resting state.

• Optimizing Sleep Quality: Experimental data indicates PS150 not only shortens sleep latency (time to fall asleep) but significantly prolongs deep sleep and regulates circadian rhythms (biological clock), improving sleep disorders caused by stress or caffeine.

• Safe and Burden-Free: As a probiotic, PS150 possesses a high safety profile, free from the addiction risks or side effects often associated with common sleeping pills.

  
  

Global Strategy: Patent Protection and Commercial Success

PS150 has performed brilliantly not only in academia but also in commercial application. The strain has already secured patent certifications in multiple countries, including Taiwan, the USA, Japan, and Malaysia. The scope of these patents covers the improvement of sleep disorders and the regulation of emotional stress.

"Winning the National Innovation Award is the greatest encouragement for Bened Biomedical’s persistence in 'Deep R&D.' We have proven that the application of probiotics is not limited to gut health but can deeply influence the central nervous system." — Enchia Tsai, Co-founder of Bened Biomedical

Bened Biomedical is committed to continuing its investment in clinical research, pushing Taiwan-developed psychobiotics onto the world stage to provide a safer, more effective solution for people globally suffering from sleep issues.