Published articles

Psychobiotic: PS128

Stress and Sleep

*Improved anxiety, stress, and insomnia in highly-stressed office workers

"Psychobiotic Supplementation of PS128 Improves Stress, Anxiety, and Insomnia in Highly Stressed Information Technology Specialists: A Pilot Study"

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Regulated dopamine and serotonin levels, improved anxiety-like and movement behaviors

"Alteration of behavior and monoamine levels attributable to Lactobacillus plantarum PS128 in germ-free mice"

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Lowered anxiety- and depression-like behaviors, regulated related dopamine and serotonin

"Psychotropic effects of Lactobacillus plantarum PS128 in early life-stressed and naïve adult mice"

Autism Spectrum Disorder

*Significant improvements in autism patients taking PS128, more than other probiotics

"Lactobacillus plantarum PS128 and Other Probiotics in Children and Adolescents with Autism Spectrum Disorder: A Real-World Experience"

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*Overall improvement in autism patients from PS128 and oxytocin combination therapy

"Probiotic and Oxytocin Combination Therapy in Patients with Autism Spectrum Disorder: A Randomized, Double-Blinded, Placebo-Controlled Pilot Trial"

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*Alleviated symptoms of autism in children

"Effects of Lactobacillus plantarum PS128 on Children with Autism Spectrum Disorder in Taiwan: A Randomized, Double-Blind, Placebo-Controlled Trial"

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Parkinson's Disease

*Improved motor function and quality of life in Parkinson's patients taking levodopa

"The Add-On Effect of Lactobacillus plantarum PS128 in Patients with Parkinson's Disease: A Pilot Study "

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Enhanced dopamine and BDNF, reduced Parkinson’s disease-like symptoms

"Lactobacillus plantarum PS128 alleviates neurodegenerative progression in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced mouse models of Parkinson's disease"

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Physical Recovery

*Benefits to exercise recovery and athletic performance in athletes

"Lactobacillus plantarum PS128 Improves Physiological Adaptation and Performance in Triathletes through Gut Microbiota Modulation"

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*Benefited oxidative stress, exercise performance, and serum BCAA levels in athletes

"The Beneficial Effects of Lactobacillus plantarum PS128 on High-Intensity, Exercise-Induced Oxidative Stress, Inflammation, and Performance in Triathletes"

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Other

Regulated dopamine and reduced Tourette syndrome-like behavior

"Lactobacillus plantarum PS128 ameliorates 2,5-Dimethoxy-4-iodoamphetamine-induced tic-like behaviors via its influences on the microbiota-gut-brain-axis"

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Ameliorated gastrointestinal symptoms

"Lactobacillus plantarum PS128 Ameliorated Visceral Hypersensitivity in Rats Through the Gut-Brain Axis"

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Confirmed safe and non-toxic

"Toxicity Studies of Lactobacillus plantarum PS128™ Isolated from Spontaneously Fermented Mustard Greens"

Psychobiotic: PS23

Aging (Memory and Muscle)

Ameliorated age-related loss of mitochondrial function, muscle mass, and strength

"Lactobacillus paracasei  PS23 decelerated age-related muscle loss by ensuring mitochondrial function in SAMP8 mice"

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Lessened cognitive, behavioral, and physiological signs of aging

"Lactobacillus paracasei PS23 Delays Progression of Age-Related Cognitive Decline in Senescence Accelerated Mouse Prone 8 (SAMP8) Mice"

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Improved gut microbiota composition and GI function related to cognitive and muscle loss

"Lactobacillus paracasei PS23 Effectively Modulates Gut Microbiota Composition and Improves Gastrointestinal Function in Aged SAMP8 Mice"

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Depression and Anxiety​

Diminished anxiety- and depression-like symptoms, stress hormones, and inflammation

"Lactobacillus paracasei  PS23 reduced early-life stress abnormalities in maternal separation mouse model"

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Raised BDNF levels, reduced depression- and anxiety-like behaviors and stress hormone

"Antidepressant-like activities of live and heat-killed Lactobacillus paracasei PS23 in chronic corticosterone-treated mice and possible mechanisms"

Immunity & Digestive Metabolism: A17, K37, K21

Improved immune responses

"Immunomodulatory Activity of Lactococcus lactis A17 from Taiwan Fermented Cabbage in OVA-Sensitized BALB/c Mice"

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Modulated allergic reactions

"Oral administration of heat-inactivated Lactobacillus plantarum K37 modulated airway hyperresponsiveness in ovalbumin-sensitized BALB/c mice"

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Lowered body weight and regulated lipid markers

"Effect of Lactobacillus plantarum Strain K21 on High-Fat Diet-Fed Obese Mice"