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How does the neurologically active PS128 probiotic work?

1 November 2022 | by Prof. Ying-Chieh Tsai, Ph.D.

The organ with the second largest number of nerve cells besides your brain is your gut. Often called the “2nd brain”, the enteric nervous system connects to the central nervous system via the vagus nerve and other pathways. This so-called gut-brain axis (GBA) enables two-way communication between the brain and the intestines. It also includes your gut contents: the trillions of bacteria, yeasts and viruses of the gut microbiota.

The GBA is of special interest to people with Parkinson’s disease (PD) and their loved ones. It plays a role both in the development of PD. Also, certain neurologically active probiotics appear to utilize the GBA to modulate levels of neurotransmitters like dopamine in the brain. In this article I’ll discuss how one of those unique probiotics may do that.



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