PS23 & VigorBiotics
Psychobiotics

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Lacticaseibacillus (Lactobacillus)
paracasei
PS23™

  • Isolated from the human gut

  • Safe (GRAS pending, L. paracasei species EFSA QPS)

  • Vegan, kosher and halal

  • Clinically studied for safety and effectiveness

  • VigorBiotics (PS23 strain postbiotics): shelf-stable, no need for refrigeration, resistant to harsh GI conditions, can be added to any food, beverage, or supplement product

Image by Robina Weermeijer

Key functions & benefits

  • Boosts mitochondria function to fight adverse effects of aging

  • Replenishes BDNF (brain-derived neurotrophic factor) for memory and cognition

  • Helps maintain muscle strength and increases protein uptake

  • Balances dopamine (motivation) and serotonin (mood)

  • Reduces cortisol (stress) levels throughout the body

  • Lowers inflammation, raises antioxidants and strengthens immune function

  • Improves GI function and healthy gut microbiota

Ongoing research

The development of our strains is guided by scientific findings. PS23's benefits for memory and muscle aging have been demonstrated preclinically, and many of the results have already been published. Multiple clinical studies are also currently underway in labs around the world. 

How psychobiotics work

Our "microbiota-gut-brain axis" is made up of gut microbes and the two-way connection between our enteric (intestinal) and central nervous systems. Probiotics interact with other gut microbes, our food, and all of the other cells and molecules in our GI tract. Resulting health benefits include SCFAs (short-chain fatty acids), balanced neurotransmitters and hormones, and modified cellular gene expression.

Using multiple pathways from within our gut, PS23 can benefit multiple symptoms of aging, including memory and muscle decline. This may happen due to improved mitochondria health, enhanced nervous system function (including adjusted BDNF, dopamine, serotonin, and cortisol levels), or modulated ghrelin hormone (which may preserve muscle and increase protein absorption).

It was discovered that even after being killed by heat, PS23 postbiotics (VigorBiotics) are still very beneficial. VigorBiotics expand the range of applications of this incredible strain.

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More about VigorBiotics

More information on the strength of postbiotics and the benefits and potential applications of VigorBiotics.